Promotion: 25% off Collagen Type I ELISA
December Promotion: 25% off Collagen Type I ELISA (Catalog M036007). Promotion code SAEXP.
Collagen Type I (CI) is the most abundant protein and is found in the skin, connective tissue, tendons, ligaments, cornea, invertebral discs and bone. It is encoded by the genes COL1A1 and COL1A2 and is formed inside (along the rough endoplasmic reticulum) and outside (by procollagen peptidase and bound by fibronectin and integrin) the cell. Individual collagen molecules are cross-linked to one another within these fibrils. The formation of cross-links results in very strong type I collagen fibrils, which are found in the spaces around cells. Collagen Type I is involved in many human diseases such as fibrosis, osteoporosis, cancer and atherosclerosis.