Tumor necrosis Factor Alpha (TNFa) ELISAs

Tumor necrosis factor alpha (TNF-alpha) is associated with numerous diseases due to its role in inflammation and autoimmunity that include rheumatoid arthritis (RA), inflammatory bowel disease (IBS), psoriasis, and multiple sclerosis (MS).

TNF-alpha is a potent cytokine with a myriad of innate immune anti-tumor
properties. TNF-α has a critical role in the bone and cartilage damage
associated with rheumatoid arthritis (RA). TNF-alpha may be involved in the
pathogenesis and/or progression of gestational diabetes mellitus (GDM).

TNF-alpha is expressed in myocardium during compensated pressure-overload
hypertrophy and contributes to postischemic myocardial dysfunction. The
serum levels of TNF-α were also significantly elevated in active WG
(Wegener’s granulomatosis) in the late stages of HIV-associated disease and
in the spinal cord of arthritic patients.

For the quantitative determination of TNF-alpha in serum, plasma and cell
culture supernate samples, the following ELISAs for different species are
available:

TNF-alpha (human) ELISA

TNF-alpha (mouse) ELISA

TNF-alpha (rat) ELISA