Collagen Type I ELISA
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The Human Collagen Type I (CI) ELISA kit is used to measure type I collagen levels from human cells.
Overview
Collagen Type I (CI) is the most abundant protein and is found in the skin, connective tissue, tendons, ligaments, cornea, invertebral discs and bone. It is encoded by the genes COL1A1 and COL1A2 and is formed inside (along the rough endoplasmic reticulum) and outside (by procollagen peptidase and bound by fibronectin and integrin) the cell. Individual collagen molecules are cross-linked to one another within these fibrils. The formation of cross-links results in very strong type I collagen fibrils, which are found in the spaces around cells. Collagen Type I is involved in many human diseases such as fibrosis, osteoporosis, cancer and atherosclerosis.
Related Terms/Symbols:
- COL-1
- COL1A1
- COL1A2
- Alpha 1 type I collagen
- Alpha 2 type I collagen
- Collagen alpha 1 chain type I
- Collagen type I alpha 1
- Collagen type I alpha 2
- Ol4
- Osteogenesis imperfecta
- Pro alpha 1 collagen type I
- Type I procollagen
- Ehlers-Danlos Syndrome
- osteoporosis
- pro-α2(I) chain
- CO1A2_HUMAN
Data/Specifications
Species: human
Sample Type: human cells
Sample Preparation: collagen must be solubilized
Sample Size: 100 uL
Standard Curve Range: 0.062 - 5 µg/mL
Sensitivity: 0.035 µg/mL
Assay Length: <3 hrs