Collagen Type II Antibody ELISA, Mouse IgG2a
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Collagen type II (CII) antibody ELISA kit is used to measure IgG2a antibodies generated against the species of type II collagen used in the induction of arthritis in mice. The ELISA comes with a pre-coated plate to the species of collagen type II used for the induction of arthritis.
| Select from the following: | Catalog # |
| anti-Bovine CII | M036002-B |
| anti-Chicken CII | M036002-C |
| anti-Human CII | M036002-H |
| anti-Mouse CII | M036002-M |
| anti-Porcine CII | M036002-P |
| anti-Rat CII | M036002-R |
Overview
The Collagen-induced arthritis (CIA) model is one of the most widely used models for the study of Rheumatoid Arthritis (RA). Collagen type II (CII) in adjuvant is used to induce arthritis by triggering autoreactive B cells, which play an important role in the development of arthritis. This B cell response to CII is strictly T cell dependent, where the B cells predominantly switch isotype to IgG.
Symbols/Related Terms:
- COL-2
- type II collagen antibody ELISA
- COL2A1
- pro-alpha 1(II) chain
Data/Specifications
Species: mouse
Sample Type: serum
Sample Preparation: dilute 1:100
Sample Size: 100 uL
Standard Curve Range: 1.56 - 25 ng/mL
Sensitivity: <0.79 ng/mL
Assay Length: 2.75 hrs
Literature/Support
How It Works
