Catalog Number:
5043020-100
Human, recombinant ST2 protein for in vitro assays.
Overview
Overview:
The recombinant ST2 comprises a 310 amino acid fragment (19-328) corresponding to the
soluble ST2 coding sequence and is expressed in E. coli with an amino-terminal hexahistidine
tag.
The ST2 gene is a member of the IL-1 receptor family, encoding a transmembrane protein with a
structure similar to IL-1R1. A soluble form of the protein (ST2) is produced from the same gene
by alternative splicing and is reported to be expressed in several cell types including fibroblasts
and mast cells. Soluble ST2 has been reported to act as a negative regulator of Th2 cytokine
production and elavated levels have been reported in several disease states and conditions
including asthma, sepsis, and myocardial infarction.
Data/Specifications
Data/Specifications:
Format: liquid
Concentration: 0.15 mg/mL
Purity: > 95% by SDS-PAGE
Storage: The protein is stable until the expiry date when stored at -20 °C. Repeated freezing and
thawing should be avoided.