Blog

Nov 26, 2018

Vascular endothelial growth factor (VEGF-165) is a heparin-binding homodimeric glycoprotein involved in embryonic vasculogenesis and angiogenesis. VEGF-165 is released by many cell populations, including fibroblasts, monocytes, macrophages and lymphocytes. Among VEGF isoforms, VEGF-165 is the...

Sep 24, 2018

Immunoglobulin D (IgD) is an antibody isotype that is found primarily on mature B cells as part of the B cell receptor (BCR) complex.  Clustering of the BCR due to antigen binding leads to activation of B cells that can result in a number of outcomes including proliferation, differentiation...

Sep 28, 2017

IL-33 is mainly expressed by fibroblasts, epithelial cells and endothelial cells. It is the ligand for orphan receptor, ST2. IL-33-ST2 plays a dual role, in some cases promotes Th2 cells and in other cases...

Jan 23, 2017

Arthritis PathologyRheumatoid arthritis (RA) is a chronic systemic autoimmune disease that affects approximately 1% of the...

Feb 22, 2016

Allergic asthma is the most common form of asthma.  In allergic asthma, the body initiates an immune response to an allergen such as pet dander, dust-mites, mold or pollen that results in IgE antibodies.  This process is commonly referred to as allergic sensitization.  Most...

Dec 4, 2015

Stress can be physical, emotional or psychological. Depending on the pressures you are facing it can have varying effects on your body. When stressful situations occur your body releases stress hormones that give you the ability to fight back to intensify your concentration and your reaction...

Apr 7, 2015

Zurich, Switzerland, April 7, 2015 – MD Biosciences, a global biotechnology company focused in neuroscience research, announces the launch of its new NeuroFreeze media for the freezing and culturing of rat...

Feb 11, 2015

Highly purified collagen type II is important for the induction of arthritis. The rate of incidence is a sore topic among many that are running the collagen induced arthritis model given disease incidence as low as 50% is not uncommon.  The purity of the collagen, adjuvant quality, emulsion...

Jan 16, 2014

The citrullination of proteins is a post-translational modification where peptidyl arginine residues are converted to peptidyl citrulline by a family of enzymes called peptidyl arginine deiminases (PADs). Citrullination can be found in multiple tissue types and has been shown to occur in both...