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Aug 18, 2020

EAE Research Model of Multiple Sclerosis Multiple Sclerosis (MS) is a demyelinating disease of the central nervous system (CNS) that results in motor, sensory and cognitive impairment. MS is one of the most common disabling neurological diseases in young...

Jul 1, 2020
Categorization of proteoglycans depends on the nature of their glycosaminoglycan chains (chondroitin sulfate, dermatan sulfate, heparan sulfate and keratan sulfate), and is also characterized by size. 
Jun 2, 2020

Joint disease research focused on proteoglycans began in the 1950s and has evolved from the early discovery of molecules to the study of their normal biological function and...

Mar 11, 2020

The OVA-IgE ELISA offers researchers sensitive, reproducible, accurate and reliable results for the measurement of OVA specific IgE in mouse serum and cell culture supernate samples. The kit is ready-to-use with all necessary reagents and can be completed in under 2.5 hours, requires small test...

Jul 2, 2019

Collagen-induced arthritis (CIA) in mice is widely used as an experimental model for rheumatoid arthritis. Initial symptoms of inflammation in the CIA model occur at...

Jun 12, 2019

Stress can be physical, emotional or psychological. Depending on the pressures you are facing it can have varying effects on your body. When stressful situations occur your body...

Nov 26, 2018

Vascular endothelial growth factor (VEGF-165) is a heparin-binding homodimeric glycoprotein involved in embryonic vasculogenesis and angiogenesis. VEGF-165 is released by many cell populations, including fibroblasts, monocytes, macrophages and lymphocytes. Among VEGF isoforms, VEGF-165 is the...

Sep 24, 2018

Immunoglobulin D (IgD) is an antibody isotype that is found primarily on mature B cells as part of the B cell receptor (BCR) complex.  Clustering of the BCR due to antigen binding leads to activation of B cells that can result in a number of outcomes including proliferation, differentiation...

Sep 28, 2017

IL-33 is mainly expressed by fibroblasts, epithelial cells and endothelial cells. It is the ligand for orphan receptor, ST2. IL-33-ST2 plays a dual role, in some cases promotes Th2 cells and in other cases...