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Featured Publication in Focus: Bone Metabolism & PTH
Jan 11, 2021

Featured Publication in Focus: Bone Metabolism & PTH Vitamin D status and parathyroid hormone relationship in adolescents and its association with bone health parameters: analysis of the Northern Ireland Young Heart’s Project

T R Hill, A A Cotter, S Mitchell, C A Boreham, W...

EAE Research Model of Multiple Sclerosis
Oct 22, 2020

EAE Research ...

Collagen Induced Arthritis: an Experimental Model for Rheumatoid Arthritis (RA)
Sep 10, 2020

 

EAE Research Model of Multiple Sclerosis
Aug 18, 2020

EAE Research Model of Multiple Sclerosis Multiple Sclerosis (MS) is a demyelinating disease of the central nervous system (CNS) that results in motor, sensory and cognitive impairment. MS is one of the most common disabling neurological diseases in young...

Proteoglycan in Articular Cartilage
Jul 1, 2020
Categorization of proteoglycans depends on the nature of their glycosaminoglycan chains (chondroitin sulfate, dermatan sulfate, heparan sulfate and keratan sulfate), and is also characterized by size. 
Aggrecan and Joint Disease
Jun 2, 2020

Joint disease research focused on proteoglycans began in the 1950s and has evolved from the early discovery of molecules to the study of their normal biological function and...

IgE Mediated Respiratory Immune Response
Mar 10, 2020

The OVA-IgE ELISA offers researchers sensitive, reproducible, accurate and reliable results for the measurement of OVA specific IgE in mouse serum and cell culture supernate samples. The kit is ready-to-use with all necessary reagents and can be completed in under 2.5 hours, requires small test...

Collagen Antibody-Induced Arthritis (CAIA): a shorter, more synchronized alternative to the classic CIA model
Jul 2, 2019

Collagen-induced arthritis (CIA) in mice is widely used as an experimental model for rheumatoid arthritis. Initial symptoms of inflammation in the CIA model occur at...

Stress and Autoimmune Disease: the role of adrenocorticotropic hormone (ACTH)
Jun 12, 2019

Stress can be physical, emotional or psychological. Depending on the pressures you are facing it can have varying effects on your body. When stressful situations occur your body...

IL-33 in asthma: application note using T1/ST2 antibody
Sep 28, 2017

IL-33 is mainly expressed by fibroblasts, epithelial cells and endothelial cells. It is the ligand for orphan receptor, ST2. IL-33-ST2 plays a dual role, in some cases promotes Th2 cells and in other cases...