Keratan Sulfate Antibody
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Keratan sulfate (KS) monoclonal antibody (mouse, clone 5D4) used to detect KS type I epitopes and KS type II epitopes.
Overview
Keratan Sulfate (KS) is a proteoglycan found in cornea (KS type I), cartilage and bone (KS type II). It’s KS chains are attached to extracellular matrix proteins or core proteins, which include lumican, keratocan, mimecan, fibromodulin, PRELP, osteoaheran and aggrecan. In the joints, keratan sulfate acts as a cushion to protect against mechanical shock. This monoclonal antibody has been raised against sulfated oligosaccharide present in corneal (KS I) and skeletal keratan sulfate (KS II).
Related Terms/Symbols:
- Keratan sulfate proteoglycans
- KS
- KS Type I
- KS Type II
Data/Specifications
Immunogen: Keratan sulfate
Clone: 5D4
Isotype: IgG
Host: Mouse
Specificity: Highly sulfated keratan sulfate glycosaminoglycan chaines in both Type I and Type II KS.
Purity: Affinity purified
Form: Liquid
Storage: -20° C
Literature/Support
Keratocan Sulfate Antibody Insert (PDF)
Joint Disease and Aggrecan (blog post)
How To Use
Applications
ELISA
Western Blot
Immunohistochemistry
Technical Notes
No enzyme pretreatment required.