Complete Freund's Adjuvant, 4 mg/mL
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Complete Freund's Adjuvant (CFA or FCA) is 4 mg/ml M. Tuberculosis (non-viable) in mineral oil.
Overview
Complete Freund’s Aduvant (CFA or FCA) is widely used in immunological research for the
preparation of antigen-adjuvant emulsions in laboratory animal studies. CFA contains cell wall
components of heat killed Mycobacterium tuberculosis and is often used for the initial injection
that stimulates an enhanced immune response.
Data/Specifications
Format: Tan liquid with particles.
Composition: 4 mg/mL M. Tuberculosis (non-viable) in mineral oil.
Application: For in-vivo/in-vitro studies.
Storage: Keep tightly closed. Store at 2-8 °C.
Literature/Support
References/Citations:
Alvarez, P., Augustín, J. J., Tamayo, E., Iglesias, M., Acinas, O., Mendiguren, M. A., ... & Merino, R. (2020). Therapeutic effects of anti-Bone Morphogenetic Protein and Activin Membrane-Bound Inhibitor treatment in psoriasis and arthritis. Arthritis & Rheumatology.
Poolman, T. M., Gibbs, J., Walker, A. L., Dickson, S., Farrell, L., Hensman, J., ... & Rattray, M. (2019). Rheumatoid arthritis reprograms circadian output pathways. Arthritis Research & Therapy, 21(1), 47.
Chuang, H. C., Chen, Y. M., Chen, M. H., Hung, W. T., Yang, H. Y., Tseng, Y. H., & Tan, T. H. (2019). AhR–ROR-γt complex is a therapeutic target for MAP4K3/GLKhighIL-17A high subpopulation of systemic lupus erythematosus. The FASEB Journal, 33(10), 11469-11480.