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MD Biosciences, Bioproducts division introduces an antiserum to mouse IgD to stimulate the B cell activation

Immunoglobulin D (IgD) is an antibody isotype that is found primarily on mature B cells as part of the B cell receptor (BCR) complex.  Clustering of the BCR due to antigen binding leads to activation of B cells that can result in a number of outcomes including proliferation, differentiation or tolerance.The ability to activate B cells in a research setting using polyclonal antisera recognizing anti-IgD is useful for the study of B cell function (Finkelman, et al., 1985; Nguyen, et al., 2014).