Product Insert:
ACTH ELISA Insert (PDF)
Articles/FAQ:
Stress and Autoimmune Disease: the role of ACTH (blog post)
ELISA Data Reduction Guide
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| References/Citations: | How the ACTH ELISA was used: |
The hypothermic response to bacterial lipopolysaccharide critically depends on brain CB1, but not CB2 or TRPV1, receptors
Alexandre, A.S. et al., (2011) J Physiol. 589:2415 | Measure the concentration of ACTH in plasma obtained from control rats (saline) and LPS-induced hyperthermia rats.
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Thymocyte-Synthesized Glucocorticoids Play a Role in Thymocyte Homeostasis and Are Down-Regulated by Adrenocorticotropic Hormone
Shengjun Qiao et al., Endocrinology, Sep 2009; 150: 4163 - 4169. | Measure the concentration of ACTH in sera obtained from C57BL/6 wild-type mice and genetically modified mice. |
Plasma Osteopontin Modulates Chronic Restraint Stress-Induced Thymus Atrophy by Regulating Stress Hormones: Inhibition by an Anti-Osteopontin Monoclonal Antibody
Kathryn X. Wang et al., J. Immunol., Feb 2009; 182: 2485 - 2491. | Measure the level of ACTH in plasma obtained from wild-type and knock-out BALB/c mice under chronic restraint stress conditions. |
Complex Role of the Mitochondrial Targeting Signal in the Function of Steroidogenic Acute Regulatory Protein Revealed by Bacterial Artificial Chromosome Transgenesis in Vivo
Goro Sasaki et al., Mol. Endocrinol., Apr 2008; 22: 951 - 964. | Measure plasma ACTH levels of 8-wk old mice of different genotypes. Blood was collected by cardiac puncture and ACTH was measured in pg/ml units. |
Inhibition of brain proinflammatory cytokine synthesis reduces hypothalamic excitation in rats with ischemia-induced heart failure
Yu-Ming Kang et al., Am J Physiol Heart Circ Physiol, Jul 2008; 295: H227 - H236. | Measure plasma ACTH levels in Sprague-Dawley rats. Rats were subject to vehicle treatment in heart failure vs SHAM models. Blood was collected in chilled EDTA tubes, separated and stored at -80C. |
Electroacupuncture activates corticotrophin-releasing hormone-containing neurons in the paraventricular nucleus of the hypothalammus to alleviate edema in a rat model of inflammation
Aihui Li, et al. BMC Complement Altern Med. 2008; 8:20 | Measure plasma ACTH levels in male Sprague-Dawley rats. Plasma was prepared from blood centrifuged at (1310 g) for 15 minutes at 4 C, collected and stored at -80 C. Rats underwent various experimental treatments including electroacupuncture and inflammation. |
Lesions of the anteroventral third ventricle region exaggerate neuroendocrine and thermogenic but not behavioral responses to a novel environment
Douglas G. Whyte and Alan Kim Johnson Am J Physiol Regulatory Integrative Comp Physiol, Jan 2007; 292: R137 - R142. | Measure plasma ACTH levels of male Sprague Dawley rats. Blood was collected in EDTA collection tubes, centrifuged at 1,000 g for 15 minutes at 4C, collected and stored at -80C. Rats were studied in SHAM and anteroventral third ventricle (AV3V) ablation models. |
Neuroendocrine profiling in inherited stress-induced arterial hypertension rat strain with stress-sensitive arterial hypertension
A L Markel et al., J. Endocrinol., Dec 2007; 195: 439 - 450. | Measure plasma ACTH levels in rats. Blood was collected in ice-cold EDTA-coated tubes, centrifuge and collected for storage at -70C. Rats investigated were ISIAH and WAG strains under stress conditions. |
The Effects of SOM230 on Cell Proliferation and Adrenocorticotropin Secretion in Human Corticotroph Pituitary Adenomas
Dalia L. Batista et al., J. Clin. Endocrinol. Metab., Nov 2006; 91: 4482 - 4488. | Measure ACTH levels in media from the primary cell culture of human corticotroph adenomas obtained from Cushing's disease patients that underwent transsphenoidal surgery (tumor samples). |
