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Jan 16, 2014

The citrullination of proteins is a post-translational modification where peptidyl arginine residues are converted to peptidyl citrulline by a family of enzymes called peptidyl arginine deiminases (PADs). Citrullination can be found in multiple tissue types and has been shown to occur in both...

Oct 7, 2013

Rat insulin is a pancreatic hormone whose molecular weight is about 6000 Da. It is a protein composed of two polypeptide chains, a shorter A-chain of twenty-one residues and a longer B-chain of thirty. The two chains are connected by two disulphide (-S-S-) linkages, while a third such linkage...

Aug 30, 2013

Tumor necrosis factor alpha (TNF-alpha) is associated with numerous diseases due to its role in inflammation and autoimmunity that include rheumatoid arthritis (RA), inflammatory bowel disease (IBS), psoriasis, and multiple sclerosis (MS).

TNF-alpha is a potent cytokine with a myriad...

Jul 19, 2011

IL-33/ST2 signaling pathway, ST2 antibodiesST2 (also known as T1) is a...

Apr 25, 2011

A recent publication using rabbit anti-mouse polyclonal antibody for immunoblotting collagen extracted from cervical tissue of pregnant and non-pregnant mice. The aim of the study is to gain a...

Mar 2, 2011

New Product Release: NSAID Antibodies

NSAID Antibodies

Feb 16, 2011

New publication citing Collagen Type II: A Virus-Like Particle-Based Anti-Nerve Growth Factor Vaccine Reduces Inflammatory Hyperalgesia: Potential Long-Term...

Feb 1, 2011

C57Bl/6 is a common background for generating genetically modified strains for use in in vivo models of arthritis. While these strains are commonly used, they are also known for requiring larger amounts of induction reagents, present with...

Jan 10, 2011

K/BxN mice spontaneously develop a severe, chronic, progressive inflammatory arthritis at about 27 days of age. They develop auto-antibodies recognizing glucose-6-phosphate isomerase. Serum from these animals when transferred to recipient animals induce arthritis. The mechanism of action...