Substance P ELISA
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The Substance P ELISA kit is designed to measure Substance P levels in human, mouse and rat samples.
Overview
Substance P is a neuropeptide that functions as a neurotransmitter and as a neuromodulator, playing a criticial role in pain perception. It is found in the brain and spinal cord, and is associated with inflammatory processes in the joints, causing arthritic pain, as well as low back pain and fibromyalgia. Substance P and other neuropeptides can be released from sensory nerve fibers in the skin, muscle and joints causing a local inflammatory response to certain types of infection or injury.
Data/Specifications
Species: human, mouse, rat
Sample Type: serum, plasma
Sample Preparation: plasma extraction
Sample Size: 50 uL
Standard Curve Range: 0.04 - 25 ng/mL
Sensitivity: 0.04 ng/mL
Assay Length: 4 hrs
Literature/Support
Substance P Insert (PDF)
| References/Citations: | How the Substance P ELISA Kit was used: |
Experimental colitis triggers the release of substance P and calcitonin gene-related peptide in the urinary bladder via TRPV1 signaling pathways. | Measure the concentration of substance P in the urinary bladder of Sprague-Dawley rats. |
Assessment of antidepressant and anxiolytic properties of NK1 antagonists and Substance P in Wistar Kyoto rats | Measure basal plasma and hypothalamic levels of substance P in an animal model of depression - adult male Wistar Kyoto rats and their controls, Wistar rats. |