MOG Induced EAE Model
The MOG 35-55 induced EAE model is essential for studying multiple sclerosis and other central nervous system autoimmune disorders. By inducing Experimental Autoimmune Encephalomyelitis (EAE) with MD Bioproducts highly purified MOG 35-55 peptide, researchers can explore immune responses and disease mechanisms and test new therapies. This model is critical for advancing our understanding and treatment of autoimmune diseases.
 |
Myelin Oligodendrocyte Glycoprotein ( MOG 35-55) SKU: 3038001 Size: 25 mg Purified myelin oligodendrocyte glycoprotein (MOG) for MOG-induced EAE models in mouse and rat. Multiple Sclerosis (MS) is a demyelinating disease of the central nervous system (CNS). The main characteristics of the disease are focal areas of demyelination and inflammation, however the pathogenesis is unclear. Although no animal model thus far establishes all facets of human MS, Experimental Autoimmune Encephalomyelitis (EAE) represents the model most studied for the disease. Initially brain homogenates were used as antigens for immunization. Today, myelin related proteins or peptides are used in the disease. |