Mouse IgG1 Isotype control, purified. This product supplied as 1.0 mg of purified immunoglobulin in 1.0 mL of borate buffered saline, pH 8.2.

Isotype controls are most commonly used in flow cytometry and immunohistochemistry experiments as negative controls that measure the level of non-specific background signal caused by primary antibodies. Background signal is due to Igs binding to non-specifcally to Fc receptors present on a cell surface (ex. mice antibodies binding to human leukocytes non-specifically in which investigators would want to use a mouse isotype control when working with human cells or tissues).