Collagen Type I, Mouse, 1 mg

Purified type I native mouse collagen from mouse tail tendon. Lyophilized. Reconstitute to yield 1-5 mg/mL collagen solution.    Type I collagen is the most abundant collagen and is found in...

Protein

8052005

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For research use only. Not for use in diagnostic procedures.

Purified type I native mouse collagen from mouse tail tendon. Lyophilized. Reconstitute to yield 1-5 mg/mL collagen solution. 

 

Type I collagen is the most abundant collagen and is found in connective tissues including tendon, ligament, dermis and blood vessel. It is the major component and the primary determinant of tensile strength of the extracelluar matrix (ECM). It is widely used as a thin layer on tissue-culture surfaces to enhance the attachment and proliferation of a variety of cells including endothelial cells, fibroblasts, hepatocytes, epithelial cells etc. In addition, collagen I can self-assemble into a 3-D superamolecular gel in vitro, making it an ideal biological scaffold to promote more in vivo-like cellular morphology and function.

Symbols/Related Terms:

  • COL1A1
  • COL1A2
  • osteogenesis imperfecta


    Product Insert (PDF) - Informational use only. Please refer to insert included with product.

    Data/Specifications: 

    • Reconstitution: Add 0.01-0.05 M acetic acid to yield 1-5 mg/mL collagen solution. Gentle mixing overnight at 4°C.
    • Purification: Partial pepsin digestion in acidic conditions and differential salt precipitation.
    • Source: mouse tail tendon
    • Form: lyophilized, 1 mg/vial
    • Purity:
    • Murine Collagen Type I at least 90%
    • Non- Collagen proteins below 2%
    • Storage: Collagen dissolved in acetic acid is stable at 4 °C for 1 month. Lyophilized collagen long term storage (2 years) at -20°C or lower.



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