Activin A Recombinant Protein (Human), 10ug

The human Activin A recombinant protein consists of a non-glycosylated polypeptide chain containing 137 amino acids (311-426aa). Activin A, a member of the transforming growth factor beta (TGF-β) superfamily, regulates immune...

Cell Signaling Pathways

7059024

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For research use only. Not for use in diagnostic procedures.

The human Activin A recombinant protein consists of a non-glycosylated polypeptide chain containing 137 amino acids (311-426aa).

Activin A, a member of the transforming growth factor beta (TGF-β) superfamily, regulates immune and inflammatory responses, cell death, and has a neurotrophic function crucial for brain repair. Produced by many cell types, Activin A is a disulfide-linked homodimer that binds to type I and type II serine-threonine kinase receptors, primarily signaling through SMAD2/3 proteins. This signaling regulates cell proliferation, differentiation, wound healing, apoptosis, and metabolism. Activin A plays a critical role in neuroprotection and adult neurogenesis, particularly following brain damage, by regulating spine formation and promoting neurogenesis.

 

Synonyms:

Erythroid differentiation protein, Activin Beta-A chain, FRP, Activin-A, EDF, Inihibin-Beta A chain, Inhibin-B

Product Insert (PDF) - Informational use only. Please refer to insert included with product.

Data/Specifications:

  • Presentation: This protein is supplied in 20mM Tris (pH 8.0) and 10% glycerol.
  • Volume: 10μg / vial
  • Form: Soluble
  • Host: E.coli
  • Molecular Weight: 15.2kDa
  • Purity: > 95%, as determined by SDS-PAGE


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