NRG-1 Recombinant Protein (Human), 50ug

The human NRG-1 recombinant protein consists of a single, non-glycosylated, polypeptide chain containing 61 amino acids. Heregulin-beta 1, also known as neuregulin-1 (NRG-1), is a member of the epidermal growth factor...

Cell Signaling Pathways

7059028

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For research use only. Not for use in diagnostic procedures.

The human NRG-1 recombinant protein consists of a single, non-glycosylated, polypeptide chain containing 61 amino acids.

Heregulin-beta 1, also known as neuregulin-1 (NRG-1), is a member of the epidermal growth factor (EGF) family and acts as a ligand for ErbB receptor tyrosine kinases. Derived from alternatively spliced genes (NRG1, NRG2, NRG3, and NRG4), heregulin-beta 1 is crucial for the development of the nervous system, heart, and mammary glands. It is expressed in neuronal cells and influences their growth and differentiation during development and wound healing. Heregulin-beta 1/ErbB signaling is essential for cardiovascular development and heart protection against ischemic injury, promotes invasiveness and metastasis in breast cancer cells, and supports the growth and maintenance of human embryonic stem cells.

 

Synonyms:

Neuregulin-1, NDF, HRGA, GGF2, HRG1, NRG1, GGF, HGL, SMDF, HRG, ARIA

Product Insert (PDF) - Informational use only. Please refer to insert included with product.

Data/Specifications:

  • Volume: 50μg / vial
  • Form: Lyophilized
  • Host: E.coli
  • Molecular Weight: 7.0kDa
  • Purity: > 95%, as determined by SDS-PAGE

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