The human recombinant protein consists of a single non-glycosylated polypeptide chain with 179 amino acids. The Cys at position 24 has been replaced with 2 Ile.

Sonic Hedgehog (Shh) is a crucial signaling protein in neural stem cell research, renowned for its significant role in the regulation of neural development and stem cell maintenance. Shh influences the proliferation, differentiation, and patterning of neural stem cells,guiding their development into various neural cell types. During embryonic development, Shh is essential for the formation of the neural tube and the organization of the central nervous system. In the context of neural regeneration, Shh signaling aids in repairing and replacing damaged neural tissues. Research into Shh pathways offers valuable insights into neural development and holds promise for advancing treatments for neurodegenerative diseases and brain injuries.

Synonyms:

Sonic hedgehog protein, TPT, HLP3, HPE3, SMMCI, TPTPS, MCOPCB5, SHH, HHG-1, HHG1