Activin A Recombinant Protein (Human), 10ug
The human Activin A recombinant protein consists of a non-glycosylated polypeptide chain containing 137 amino acids (311-426aa). Activin A, a member of the transforming growth factor beta (TGF-β) superfamily, regulates immune...
Cell Signaling Pathways
7059024
The human Activin A recombinant protein consists of a non-glycosylated polypeptide chain containing 137 amino acids (311-426aa).
Activin A, a member of the transforming growth factor beta (TGF-β) superfamily, regulates immune and inflammatory responses, cell death, and has a neurotrophic function crucial for brain repair. Produced by many cell types, Activin A is a disulfide-linked homodimer that binds to type I and type II serine-threonine kinase receptors, primarily signaling through SMAD2/3 proteins. This signaling regulates cell proliferation, differentiation, wound healing, apoptosis, and metabolism. Activin A plays a critical role in neuroprotection and adult neurogenesis, particularly following brain damage, by regulating spine formation and promoting neurogenesis.
Synonyms:
Erythroid differentiation protein, Activin Beta-A chain, FRP, Activin-A, EDF, Inihibin-Beta A chain, Inhibin-B
Product Insert (PDF) - Informational use only. Please refer to insert included with product.
Data/Specifications:
- Presentation: This protein is supplied in 20mM Tris (pH 8.0) and 10% glycerol.
- Volume: 10μg / vial
- Form: Soluble
- Host: E.coli
- Molecular Weight: 15.2kDa
- Purity: > 95%, as determined by SDS-PAGE
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