Keratan Sulfate Antibody, 100 ug
Keratan sulfate (KS) monoclonal antibody (mouse, clone 5D4) used to detect KS type I epitopes and KS type II epitopes. Liquid. Store at -20° C. Keratan Sulfate (KS) is a proteoglycan...
Antibodies
1042010
Keratan sulfate (KS) monoclonal antibody (mouse, clone 5D4) used to detect KS type I epitopes and KS type II epitopes. Liquid. Store at -20° C.
Keratan Sulfate (KS) is a proteoglycan found in cornea (KS type I), cartilage and bone (KS type II). ItÕs KS chains are attached to extracellular matrix proteins or core proteins, which include lumican, keratocan, mimecan, fibromodulin, PRELP, osteoaheran and aggrecan. In the joints, keratan sulfate acts as a cushion to protect against mechanical shock. This monoclonal antibody has been raised against sulfated oligosaccharide present in corneal (KS I) and skeletal keratan sulfate (KS II).
Related Terms/Symbols:
- Keratan sulfate proteoglycans
- KS
- KS Type I
- KS Type II
References/Citations:
Caterson B, Christner JE & Baker JR (1983). Identification of a monoclonal antibody that specifically recognizes corneal and skeletal keratan sulfate. Monoclonal antibod- ies to cartilage proteoglycan. J Biol Chem. 258(14): 8848-54.
Thonar EJ, Lenz ME, Klintworth GK, Caterson B, Pachman LM, Glickman P, Katz R, Huff J & Kuettner KE (1985). Quantification of keratan sulfate in blood as a marker of cartilage catabolism. Arthritis & Rheum. 28(12): 1367-76.
Mehmet H, Scudder P, Tang PW, Hounsell EF, Caterson B & Feizi T (1986). The anti- genic determinants recognized by three monoclonal antibodies to keratan sulphate involve sulphated hepta- or larger oligosaccharides of the poly(N-acetyllactosamine) series. Eur J Biochem. 157(2): 385-91.
Funderburgh JL, Caterson B & Conrad GW (1987). Distribution of proteoglycans antigenically related to corneal keratan sulfate proteoglycan. J Biol Chem. 262(24):11634-40.
Rees SG, Flannery CR, Little CB, Hughes CE, Caterson B & Dent CM (2000). Catabolism of aggrecan, decorin and biglycan in tendon. Biochem J. 350: 181-188.
Young RD, Akama TO, Liskova P, Ebenezer ND, Allan B, Kerr B, Caterson B, Fukuda MN, Quantock AJ (2007a). Differential immunogold localisation of sulphated and unsul- phated keratan sulphate proteoglycans in normal and macular dystrophy cornea using sulphation motif-specific antibodies. Histochem Cell Biol. 127(1):115-20
Young RD, Gealy EC, Liles M, Caterson B, Ralphs JR & Quantock AJ (2007b). Keratan sulfate glycosaminoglycan and the association with collagen fibrils in rudimen- tary lamellae in the developing avian cornea. Invest Ophthalmol Vis Sci. 2007 Jul;48(7):3083-8.
Hayes AJ, Hall A, Brown L, Tubo R & Caterson B (2007). Macromolecular organization and in vitro growth characteristics of scaffold-free neocartilage grafts. J Histochem Cytochem. 55(8):853-66.
Hayes AJ, Hughes CE & Caterson B (2008). Antibodies and immunohistochemisrty in extracellular matrix research. Methods 45: 10-21
Product Insert (PDF) - Informational use only. Please refer to insert included with product.
Data/Specifications:
- Immunogen: Keratan sulfate
- Clone: 5D4
- Isotype: IgG
- Host: Mouse
- Specificity: Highly sulfated keratan sulfate glycosaminoglycan chaines in both Type I and Type II KS.
- Purity: Affinity purified
- Form: Liquid
- Storage: -20° C
Related Products
Additional products you might interested in.
-
Complete Freund's Adjuvant, 4 mg/mL (5 mL)Complete Freund's Adjuvant (CFA or FCA) is 4 mg/ml M. Tuberculosis (non-viable) in mineral oil. For in-vivo/in-vitro studies. Typically used for th...
-
T1/ST2 (IL-33 R) Mouse, Monoclonal Antibody, PE Conjugated, 0.1 mLMouse T1/ST2 (IL-33 R) PE conjugated monoclonal antibody (Clone DJ8, Host / Isotype Subclass: Rat IgG1, light chain not isotyped) for the identific...
-
T1/ST2 (IL-33 R) Mouse, Monoclonal Antibody, Biotinylated, 0.5 mLMouse T1/ST2 (IL-33 R) biotinylated monoclonal antibody (Clone: DJ8, Host / Isotype Subclass: Rat IgG1, light chain not isotyped) for the identific...
-
Lipopolysaccharide (LPS), 5.0 mgHighly purified LPS for in vivo and in vitro use. Lipopolysaccharides (LPS), also known as lipoglyans and endotoxins, are large molecules consis...
-
T1/ST2 (IL-33R) Mouse, Monoclonal Antibody, FITC, 0.5 mLMouse T1/ST2 (IL-33 R) FITC conjugated monoclonal antibody (Clone: DJ8, Host / Isotype Subclass: Rat IgG1, light chain not isotyped) for the identi...
-
Aggrecan Antibody, C-terminal neoepitope NITEGE, 100 ugAggrecan monoclonal antibody to C-terminal neoepitope NITEGE (mouse, clone BC-13). This aggrecan degradation product usually remains within the tis...
-
ArthritoMab™ Antibody Cocktail for Balb/c, DBA/1, R10.RIII, 50 mgArthritoMab™ Arthritis Inducing Antibody Cocktail is a cocktail of 4 arthritogenic monoclonal antibodies to collagen II (CII) used for inducing art...
-
Collagen Type II, Chicken, Soluble, 2 mg/mLHighest quality (>99%) Collagen type II (CII) protein, purified from chicken sternum, for the induction of arthritis in the Collagen-Induced Art...
-
Goat anti-Mouse IgD, Antiserum, 1 mLImmunoglobulin D activator for B-cells. Preservative-free for in vivo application. Immunoglobulin D (IgD) is an antibody isotype that is found prim...
-
Collagen Type II, Chicken, Lyophilized, 10 mgHighest quality (>99%) Collagen type II (CII) protein, purified from chicken sternum, for the induction of arthritis in the Collagen-Induced Art...
-
Collagen Type II, Bovine, Immunization Grade, Soluble, 2 mg/mLImmunization Grade Collagen type II (CII) protein, purified from fetal bovine articular cartilage, for the induction of arthritis in the Collagen-I...
-
Collagen Type II, Bovine, Immunization Grade, Lyophilized, 10 mgImmunization Grade Collagen type II (CII) protein, purified from fetal bovine articular cartilage, for the induction of arthritis in the Collagen-I...
-
Human Collagen Type IV, Lyophilized, 0.1mgHuman Collagen Type IV protein purified from human placenta. Collagen Type IV is a type of collagen found primarily in the skin within the basement...
-
ArthritoMab™ Antibody Cocktail for C57BL/6, TG, 50 mgArthritoMab™ Antibody Cocktail is a reformulated cocktail of 4 monoclonal antibodies for the induction of arthritis as an alternative to the widely...
-
ST2L Human, Monoclonal Antibody, Biotinylated, 200 uLHuman ST2L biotinylated monoclonal antibody (Clone: B4E6, Host / Isotype Subclass: Mouse IgG1), for the identification and purification of human t...
-
ST2L Human, Monoclonal Antibody, 200 uLHuman ST2L monoclonal antibody (Clone: B4E6, Host / Isotype Subclass: Mouse IgG1), for the identification and purification of human type 2 (Th2) ly...
-
Myelin Oligodendrocyte Glycoprotein (MOG 35-55), 25 mgPurified myelin oligodendrocyte glycoprotein (MOG) for MOG-induced EAE models in mouse and rat. Multiple Sclerosis (MS) is a demyelinating disease...
-
Lubricin Antibody, Native Bovine, 100 ugLubricin (PRG4) monoclonal antibody (mouse, clone 3A4) to detect the native form of bovine lubricin. Does not recognize reduced or denatured lubric...
-
Collagen Type I (Atelocollagen) Porcine, 30 mgHighly Purified Porcine Collagen Type I from porcine tendon. Lyophilized. Reconstitute to a concentration of 1-5 mg/mL. Type I collagen is the m...
-
Collagen Type I, Mouse, 1 mgPurified type I native mouse collagen from mouse tail tendon. Lyophilized. Reconstitute to yield 1-5 mg/mL collagen solution. Type I collagen is...
-
Collagen Type I and III, Porcine, 10 mgPurified type I & III native porcine collagen from pig’s tissue, 10 mg. Highest quality collagen for research use. Type I collagen is the mo...
-
Collagen Type I and III, Canine, 10 mgPurified type I & III canine collagen. Type I collagen is the most abundant collagen and is found in connective tissues including tendon, ligam...
-
Alpha Fetoprotein, Human, 0.1mgAlpha Fetoprotein extracted from Human Blood Cord. Alpha-fetoprotein (AFP) is a glycoprotein produced mainly by the fetal liver, yolk sac, an...
-
Fibronectin 120 kDa Fragment Cell Attachment, Human, 0.5mgFibronectin heparin binding 120 kDa fragment. Chymotryptic digest of human plasma fibronectin. The Human Fibronectin 120 kDa cell attachment fra...
-
Fibronectin 40 kDa Fragment Heparin Binding, Human, 0.5mgFibronectin heparin binding 40 kDa fragment. Chymotryptic digest of human plasma fibronectin. Heparin-binding 40 kDa fragment of human plasma...
-
Fibronectin, Human, 5mgFibronectin from human plasma. Fibronectin is a high-molecular-weight glycoprotein of the extracellular matrix that plays a crucial role in c...
-
Bovine Collagen Type VI, Lyophilized, 0.1mgBovine Collagen Type VI protein purified from bovine placenta. Collagen Type VI is the major collagenous component of microfibrils in elastic fibe...
-
Human Collagen Type V, Lyophilized, 0.1mgHuman Collagen Type V protein purified from human placenta. Collagen Type V is a fibrillar collagen. Collagen Type V is essential for the fibrilla...
-
Human Collagen Type III, Lyophilized 0.1 mgHuman Collagen Type III protein purified from human placenta. Type III collagen is a fibrillar collagen, and it consists of only one collagen α ch...
-
Human Collagen Type I, Lyophilized 0.1 mgHuman Collagen Type I protein purified from human placenta. Type I collagen is the most abundant collagen and is found in connective tissues includ...
-
Human Collagen Type II, Lyophilized 0.1 mgHuman Collagen Type II protein purified from human cartilage. Collagen Type II is a fibrillar collagen, and the main component of cartilage. Type ...
-
Complete Freund's Adjuvant, 10 mg/mL (5 mL)Complete Freund's Adjuvant (CFA or FCA) is 10 mg/ml M. Tuberculosis (non-viable) in mineral oil. Typically used to induce Adjuvant-Induced Arthriti...
-
Uromodulin Glycoprotein (UMOD, Tamm-Horsfall Glycoprotein, THP) ELISAThe MonELISA® Uromodulin Glycoprotein ELISA kit is used for the quantitative determination of Uromodulin Glycoprotein (THP) in urine and serum samp...
-
T1/ST2 (IL-33 R) Mouse, Monoclonal Antibody, 0.5 mLMouse T1/ST2 (IL-33 R) monoclonal antibody (Clone: DJ8, Host / Isotype Subclass: Rat IgG1, light chain not isotyped) for the identification and pur...
-
T1/ST2 (IL-33 R) Monoclonal Antibody, azide-free, 0.5 mLMouse T1/ST2 (IL-33 R) monoclonal antibody (Clone DJ8, Host / Isotype Subclass: Rat IgG1, light chain not isotyped), azide-free, for the identific...
-
ST2L Human, Monoclonal Antibody, FITC, 200 uLHuman ST2L FITC conjugated monoclonal antibody (Clone: B4E6, Host / Isotype Subclass: Mouse IgG1), for the identification and purification of human...
-
Rat IgG1 Isotype Control, R-PE Conjugated Antibody, 0.1 mgIsotype controls are most commonly used in flow cytometry and immunohistochemistry experiments as negative controls that measure the level of non-s...
-
Rat IgG1 Isotype Control, Purified Antibody, 0.5 mgIsotype controls are most commonly used in flow cytometry and immunohistochemistry experiments as negative controls that measure the level of non-s...
-
Rat IgG1 Isotype Control, Low endotoxin, Azide-free, 0.5 mgIsotype controls are most commonly used in flow cytometry and immunohistochemistry experiments as negative controls that measure the level of non-s...
-
Rat IgG1 Isotype Control, FITC Conjugated Antibody, 0.5 mgIsotype controls are most commonly used in flow cytometry and immunohistochemistry experiments as negative controls that measure the level of non-s...
-
Rat IgG1 Isotype Control, Biotin Conjugated Antibody, 0.5 mgIsotype controls are most commonly used in flow cytometry and immunohistochemistry experiments as negative controls that measure the level of non-s...
-
Myelin Proteolipid Protein (PLP 139-151), 15 mgPurified myelin proteolipid protein (PLP) for PLP-induced EAE models in mouse and rat. Multiple Sclerosis (MS) is a demyelinating disease of the c...
-
Mouse IgG1 Isotype Control, Purified Antibody, 1 mgMouse IgG1 Isotype control, purified. This product supplied as 1.0 mg of purified immunoglobulin in 1.0 mL of borate buffered saline, pH 8.2. Iso...
-
Mouse IgG1 Isotype Control, low endotoxin, azide-free, 0.5 mgMouse IgG1 Isotype control, Low endotoxin, azide-free. The low endotoxin, azide-free antibody is supplied as 0.5 mg purified immunoglobulin in 1.0 ...
-
Mouse IgG1 Isotype Control, FITC-conjugated Antibody, 0.1 mgMouse IgG1 Isotype control, FITC-conjugated. The fluorescein (FITC) conjugate is supplied in 1.0 mL PBS/NaN3. Store at 2 – 8 °C. Isotype controls...
-
Mouse IgG1 Isotype Control, Biotin-conjugated Antibody, 0.5 mgMouse IgG1 Isotype control, Biotin Conjugated. The biotin conjugate is supplied as 0.5 mg in 1.0 mL of PBS/NaN3. Store at 2 – 8 °C. Isotype contr...
-
Lumican, Antibody, 100 ugLumican (LUM) monoclonal antibody (mouse, clone Lum-1) to detect a protein epitope in lumican. Liquid, 1 mL/vial. Concentration: 0.1 mg/mL Lumica...
-
Lubricin Antibody, Bovine, 100 ugLubricin (PRG4) monoclonal antibody (mouse, clone 6A1) to detect superficial zone protein (SZP) from bovine articular cartilage and a non conformat...
-
Keratocan Antibody, 100 ugKeratocan (KERA) monoclonal antibody (mouse, clone Ker-1) to detect keratocan. 1 mL/vial. Concentration is 0.1 mg/mL. Normal keratocan expressio...